Beilstein J. Org. Chem.2019,15, 96–105, doi:10.3762/bjoc.15.11
should be made to improve activity after internalization of the PDC.
Overall, the investigations carried out up to this point provide a biological validation of the developed conjugate. The principally modular conjugation protocol for tubugis bears promise for further cancertargeting conjugates
Beilstein J. Org. Chem.2017,13, 1316–1324, doi:10.3762/bjoc.13.128
theranostic applications.
Keywords: BODIPY conjugates; cancertargeting; drug delivery; liposomes; natural compounds; sesquiterpene lactone trilobolide; Introduction
Targeted (smart) drug delivery is a method for specific delivering of an active compound preferentially to some cells or tissues in the human
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Graphical Abstract
Figure 1:
Chemical structures of the basic compounds used in this study.